Enzyme Histochemistry on Normal and Pathologic Paraffin-embedded Lymphoid Tissues

Laser capture microdissection of paraffin-embedded tissues.

Proteomic analysis of RCL2 paraffin-embedded tissues

Histopathological diagnosis in most of the world's hospitals is based upon formalin-fixed and paraffin-embedded (FFPE) tissues. Although this standard fixation and embedding procedure keeps the tissue in excellent form for morphological and immunohistological analysis, FFPE is inappropriate for nucleic acids and protein studies. We investigated the potential value of RCL2, a new non-toxic fixat...

Enzyme histochemistry on jejunal tissue embedded in resin.

Immunohistochemical detection of P-glycoprotein in formalin-fixed and paraffin-embedded normal and neoplastic canine tissues.

Expression of P-glycoprotein, a phylogenetically conserved integral plasma membrane protein, is implicated as one of the most important factors contributing to tumor cell multidrug resistance. Formalin-fixed, paraffin-embedded normal and neoplastic canine tissues were studied using an avidin-biotin complex technique employing three murine monoclonal antibodies (C494, C219, JSB-1) to different e...

Histochemistry in Pathologic Diagnosis

By analogy, if Sam Spicer were concerned with athletes, I think he would be the manager of a baseball team. At first glance, he seems to know who the batters are, where his players should position themselves, and what kind of pitches are needed to do the job. What is unfair is that this reader is a middle linebacker by nature and training. Histochemistry contains both the theoretical and the ap...